Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.58 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309021 | 1.00 | MAP3K14 (0.58) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| SCHEMBL29699812 | 1.00 | MAP3K14 (0.58) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| SCHEMBL29894820 | 1.00 | MAP3K14 (0.58) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| SCHEMBL29457666 | 1.00 | MAP3K14 (0.58) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| SCHEMBL819188 | 1.00 | MAP3K14 (0.58) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| Formaldehyde SCHEMBL27517296 | 0.94 | MAP3K14 (0.53) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| SCHEMBL7784019 | 0.88 | MAP3K14 (0.46) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| SCHEMBL131444 | 0.79 | ITGB2 (0.46) | MAP3K14ITGB2ICAM1ITGALMAOA | |
| SCHEMBL31296141 | 0.78 | LTB4R (0.51) | ITGB2ICAM1ITGALMAOAMAOB | |
| SCHEMBL19268289 | 0.78 | LTB4R (0.51) | ITGB2ICAM1ITGALMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018133-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ABBVIE INC. | 2024-01-18 | — | — | US | claimed |
| WO-2023160586-A1 | BENZODIHYDROPYRAN COMPOUND HAVING ANTI-HEPATITIS B VIRUS AND ANTI-CORONAVIRUS EFFECTS | 云南民族大学 | 2023-08-31 | — | — | WO | claimed |
| CN-114685251-B | Direct cross-coupling reaction method of diaryl sulfoxide and aryl bromide | 南京工业大学 | 2022-12-27 | — | — | CN | claimed |
| CN-114685251-A | Direct cross-coupling reaction method of diaryl sulfoxide and aryl bromide | 南京工业大学 | 2022-07-01 | — | — | CN | claimed |
| EP-3962899-A1 | SUBSTITUTED CYCLOLAKYLS AS MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2022-03-09 | — | — | EP | claimed |
| US-20190177862-A1 | HYDROGEN UTILIZATION AND CARBON RECOVERY | COORSTEK, INC. | 2019-06-13 | — | — | US | claimed |
| EP-3039099-B1 | METHOD FOR UPGRADING BIOMASS MATERIAL | COORSTEK INC (US) | 2019-06-12 | — | — | EP | claimed |
| CN-104788462-B | Chiral polysubstituted 4-hydroxychroman compound, and preparation method and application thereof | 中国科学院化学研究所 | 2017-02-08 | — | — | CN | claimed |
| EP-3039099-A1 | HYDROGEN UTILIZATION AND CARBON RECOVERY | Ceramatec, Inc (US) | 2016-07-06 | — | — | EP | claimed |
| CN-104788462-A | Chiral polysubstituted 4-hydroxychroman compound, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-07-22 | — | — | CN | claimed |
| US-20060004123-A1 | PHASE CHANGE INK PRINTING PROCESS | XEROX CORPORATION | 2006-01-05 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| CN-1236357-A | Aminomethylene derivatives and ultraviolet absorber comprising the same | CHEMIPRO KASEI KAISHA LTD (JP) | 1999-11-24 | — | — | CN | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0674633-A1 | BENZOPYRAN DERIVATIVES | ALKALOIDA VEGYESZETI GYAR RT (HU) | 1995-10-04 | — | — | EP | claimed |
| WO-1994014799-A1 | BENZOPYRAN DERIVATIVES | ALKALOIDA VEGYÉSZETI GYÁR RT. (HU) | 1994-07-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018133-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ATF4, ATF1, DDIT3 | MAP3K14 186/4885ITGB2 4686/4885ICAM1 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.