Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of D-Alanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 4/20 | 0.39 |
| ▸ | GABRD | O14764 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL28538824 | 1.00 | SLC7A5 (0.53) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL468681 | 1.00 | SLC7A5 (0.53) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL6160098 | 1.00 | SLC7A5 (0.53) | SLC7A5FFAR3LCKFYNTP53 | |
| D-Alanine SCHEMBL31494467 | 1.00 | SLC7A5 (0.53) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL6160093 | 1.00 | SLC7A5 (0.53) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL468682 | 1.00 | SLC7A5 (0.53) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL28967983 | 0.97 | SLC7A5 (0.50) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL28967982 | 0.97 | SLC7A5 (0.50) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL7562284 | 0.97 | SLC7A5 (0.50) | SLC7A5FFAR3LCKFYNTP53 | |
| Alanine SCHEMBL9018448 | 0.94 | LMNA (0.50) | SLC7A5FFAR3LCKFYNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793769-B2 | Compositions including acidic chelator for treatment of subterranean formations including one or more fractures | HALLIBURTON ENERGY SERVICES, INC. (US) | 2020-10-06 | — | — | US | claimed |
| US-20220372330-A1 | METHOD FOR PRODUCING POLISHING COMPOSITION | FUJIMI INCORPORATED (JP) | 2022-11-24 | — | — | US | disclosed |
| US-20220162498-A1 | METHOD FOR IMPROVED OIL RECOVERY IN SUBTERRANEAN FORMATIONS WITH CIRCUMNEUTRAL pH FLOOD | HALLIBURTON ENERGY SERVICES, INC. | 2022-05-26 | — | — | US | disclosed |
| US-10604850-B2 | Corrosion inhibition of HCL treatment fluids with environmentally compatible solvent | HALLIBURTON ENERGY SERVICES, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20180127882-A1 | Corrosion Inhibition of HCL Treatment Fluids with Environmentally Compatible Solvent | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-05-10 | — | — | US | disclosed |
| US-20110272176-A1 | PATTERN ELECTRODE MANUFACTURING METHOD AND PATTERN ELECTRODE | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20090078908-A1 | POLISHING LIQUID | FUJIFILM CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |