Sugi Predict

Sugi Predict / Compounds / SCHEMBL131476

SCHEMBL131476

SCHEMBL131476

CN(C)C(=O)CCCCC(=O)N(C)C

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.74
▸ CHRNB2 P17787 1/20 0.58
▸ CHRNB4 P30926 1/20 0.58
▸ CHRNA4 P43681 1/20 0.58
▸ LMNA P02545 1/20 0.46
▸ HTT P42858 1/20 0.42
▸ KDM4A O75164 11/20 0.40
▸ KDM4C Q9H3R0 11/20 0.40
▸ KDM5A P29375 1/20 0.40
▸ KDM7A Q6ZMT4 1/20 0.40
▸ PHF8 Q9UPP1 1/20 0.40
▸ KDM2A Q9Y2K7 1/20 0.40
▸ ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3189950 0.97 ALDH1A1 (0.70) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL5948495 0.93 ALDH1A1 (0.74) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL812501 0.89 ALDH1A1 (0.61) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL1049266 0.89 ALDH1A1 (0.61) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL630064 0.89 ALDH1A1 (0.85) ALDH1A1CHRNB2CHRNB4CHRNA4
SCHEMBL1049265 0.89 ALDH1A1 (0.61) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL1291925 0.89 ALDH1A1 (0.61) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL740728 0.87 ALDH1A1 (0.81) ALDH1A1
SCHEMBL22406917 0.87 ALDH1A1 (0.81) ALDH1A1
SCHEMBL15254336 0.87 ALDH1A1 (0.58) ALDH1A1CHRNB2CHRNB4CHRNA4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9878975-B2 Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides EVONIK DEGUSSA GMBH (DE) 2018-01-30 — — US claimed
US-5476743-A Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant XEROX CORPORATION (US) 1995-12-19 — — US claimed
EP-0304134-A2 Magnetic resin composition DSM N.V. (NL) 1989-02-22 — — EP claimed
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2026-03-31 — — US disclosed
CN-118871522-A High performance polymer composition containing carbon nanostructures 提克纳有限责任公司 2024-10-29 — — CN disclosed
CN-118435715-A EMI shielding polymer composition 提克纳有限责任公司 2024-08-02 — — CN disclosed
CN-118401534-A Flame retardant thermoplastic polymer composition 国际人造丝公司 2024-07-26 — — CN disclosed
CN-117898032-A Multilayer composite for EMI shielding 提克纳有限责任公司 2024-04-16 — — CN disclosed
CN-116769222-A Polyamide resin foam particles for fiber-reinforced resin composite core material, and fiber-reinforced resin composite 株式会社JSP 2023-09-19 — — CN disclosed
US-20220274985-A1 PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. 2022-09-01 — — US disclosed
EP-3990455-A1 PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-05-04 — — EP disclosed
US-4751272-A POLYMERIZING TRIOXANE AND CYCLIC ETHER; BORON TRIFLUORIDE CATALYST TORAY INDUSTRIES, INC. (JP) 1988-06-14 — — US disclosed
EP-0244245-A2 Process for producing oxymethylene copolymer and resinous composition TORAY INDUSTRIES, INC. (JP) 1987-11-04 — — EP disclosed
US-4634530-A Chemical modification of preformed polybenzimidazole semipermeable membrane CELANESE CORPORATION (US) 1987-01-06 — — US disclosed
EP-0097615-B1 PREPARATION OF CYANOBENZOIC-ACID ESTERS CIBA-GEIGY AG (CH) 1985-11-21 — — EP disclosed
EP-0144467-A1 Catalyst system and its use in hydrogenation of N,N-disubstituted amides to amines THE PROCTER & GAMBLE COMPANY (US) 1985-06-19 — — EP disclosed
US-4448998-A COPPER CHROMITE AND ZEOLITE THE PROCTER & GAMBLE COMPANY (US) 1984-05-15 — — US disclosed
EP-0097615-A1 Preparation of cyanobenzoic-acid esters CIBA-GEIGY AG (CH) 1984-01-04 — — EP disclosed
US-4212952-A N,N,N',N'-Tetramethyl-αω-polymethlenediamines as catalysts for the preparation of urethane foams UNION CARBIDE CORPORATION (US) 1980-07-15 — — US disclosed
EP-0013083-A1 The use of N,N,N',N'-tetramethyl-alpha-omega-polymethylene diamines as catalysts for the preparation of urethane foams, and urethane foams prepared therewith UNION CARBIDE CORPORATION (US) 1980-07-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds TLR8, MYD88, TLR6 ALDH1A1 3917/4885CHRNB2 2293/4885CHRNB4 3143/4885
US-20220274985-A1 PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS TLR4, TLR3, TLR6 ALDH1A1 4031/4885CHRNB2 1453/4885CHRNB4 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.