Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 3/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ABL2 | P42684 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403600 | 0.82 | ADORA2A (0.36) | PDE4APDE4BPDE4CPDE4DSRC | |
| SCHEMBL586526 | 0.79 | XDH (0.39) | ABL1RET | |
| SCHEMBL31403567 | 0.78 | HSD17B10 (0.40) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL31403505 | 0.78 | MAPT (0.39) | PDE4APDE4BPDE4CPDE4DOPRK1 | |
| SCHEMBL31403718 | 0.75 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL25386480 | 0.74 | ALDH1A1 (0.39) | PDE4APDE4BPDE4CPDE4DOPRK1 | |
| SCHEMBL14884084 | 0.73 | HSD17B10 (0.43) | HSD17B10L3MBTL1BRD4ABL1RET | |
| SCHEMBL18892022 | 0.71 | HSD17B10 (0.39) | HSD17B10L3MBTL1ABL1RETKDM4E | |
| SCHEMBL22533181 | 0.70 | BRD4 (0.38) | PDE4DOPRK1BRD4SRCRET | |
| SCHEMBL31386207 | 0.70 | ATM (0.35) | HSD17B10OPRK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117935-A1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | SCHERING CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |