Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | CCR2 | P41597 | 12/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13148364 | 0.87 | CCR2 (0.56) | CCR2THRBROCK1CCR5 | |
| Iodide SCHEMBL17555161 | 0.87 | CCR2 (0.55) | CCR2THRBROCK1CCR5 | |
| Hydrochloric Acid SCHEMBL2907679 | 0.87 | CCR2 (0.55) | CCR2THRBROCK1CCR5 | |
| SCHEMBL313476 | 0.79 | CCR2 (0.72) | CCR2CCR5MEN1KMT2ALMNA | |
| SCHEMBL13148354 | 0.79 | CCR2 (0.60) | RXFP1CCR2THRBCCR5 | |
| Hydrochloric Acid SCHEMBL313399 | 0.78 | CCR2 (0.70) | CCR2CCR5MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL2907331 | 0.78 | CCR2 (0.59) | RXFP1CCR2THRBCCR5 | |
| SCHEMBL13148359 | 0.78 | CCR2 (0.65) | CCR2CCR5 | |
| SCHEMBL13148508 | 0.78 | PYGL (0.62) | RXFP1CCR2MEN1KMT2A | |
| Iodide SCHEMBL17555127 | 0.78 | CCR2 (0.59) | RXFP1CCR2THRBCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799824-B2 | Quaternary salt CCR2 antagonists | ORAPHARMA, INC. (US) | 2010-09-21 | — | — | US | disclosed |