Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628808 | 0.88 | LMNA (0.41) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL13148639 | 0.85 | MPL (0.41) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL13148649 | 0.73 | RXRA (0.46) | LMNAKMT2AHPGDPPARGPPARA | |
| SCHEMBL628001 | 0.72 | LMNA (0.46) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL10029585 | 0.69 | LMNA (0.43) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL2109105 | 0.68 | PTPN11 (0.46) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL628795 | 0.67 | RXRA (0.49) | LMNAGAATSHRKMT2APPARG | |
| SCHEMBL627996 | 0.67 | S1PR1 (0.50) | LMNAGAAHPGDPPARGPPARA | |
| SCHEMBL629167 | 0.66 | RXRA (0.53) | LMNAGAATSHRKMT2AHPGD | |
| SCHEMBL629104 | 0.65 | S1PR1 (0.43) | LMNAGAATSHRKMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120741-A1 | COMPOSITIONS AND METHODS FOR MODULATING RETINOL BINDING TO RETINOL BINDING PROTEIN 4 (RBP4) | IRM LLC (US) | 2010-10-21 | — | — | WO | disclosed |