Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | IL2 | P60568 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866323 | 0.85 | EIF4E (0.43) | EIF4ECTSSCTSKAGPAT2FFAR4 | |
| SCHEMBL10029592 | 0.66 | AGPAT2 (0.42) | EIF4EAGPAT2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL629227 | 0.64 | EIF4E (0.53) | EIF4EHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19785385 | 0.64 | PDE2A (0.47) | CTSSCTSKKDM1APDE2AIL2 | |
| SCHEMBL29859465 | 0.64 | KDM1A (0.41) | CTSSCTSKAGPAT2FFAR4SMN1; SMN2 | |
| SCHEMBL28620228 | 0.62 | NR4A2 (0.48) | SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL628790 | 0.61 | NOTUM (0.49) | EIF4ECTSSCTSKKMT2ALMNA | |
| SCHEMBL628795 | 0.61 | RXRA (0.49) | KMT2APPARGPPARALMNA | |
| SCHEMBL16629821 | 0.60 | CTSS (0.47) | EIF4ECTSSCTSKAGPAT2KDM1A | |
| SCHEMBL5901540 | 0.60 | PPARG (0.46) | ALDH1A1PPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120741-A1 | COMPOSITIONS AND METHODS FOR MODULATING RETINOL BINDING TO RETINOL BINDING PROTEIN 4 (RBP4) | IRM LLC (US) | 2010-10-21 | — | — | WO | disclosed |