Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12586587 | 0.88 | CYP3A4 (0.49) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL9039455 | 0.87 | CYP3A4 (0.55) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL31638876 | 0.86 | CYP3A4 (0.63) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL31643815 | 0.84 | IDO1 (0.43) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL4155491 | 0.82 | CYP3A4 (0.47) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL12552999 | 0.82 | CYP3A4 (0.52) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL28812075 | 0.79 | CA12 (0.46) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL14094952 | 0.79 | CYP3A4 (0.68) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL29690740 | 0.79 | KMT2A (0.46) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL14511729 | 0.79 | CYP3A4 (0.56) | CYP3A4CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513440-B2 | Compositions and methods comprising analogues of radicicol A | UNIVERSITE DE STRASBOURG (FR) | 2013-08-20 | — | — | US | disclosed |
| US-20100233279-A1 | Compositions And Methods Comprising Analogues Of Radicicol A | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233279-A1 | Compositions And Methods Comprising Analogues Of Radicicol A | CSNK1A1L, CSNK1A1, ALPL | CYP3A4 3362/4885CA12 1204/4885CA1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.