SCHEMBL1315015

SCHEMBL1315015

CCCCO[Si](C)(C)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
NAAA Q02083 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 2/20 0.31
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31
EPHX2 P34913 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28434138 0.88 CYP1A2 (0.33) CYP1A2CYP2D6CYP2C19
SCHEMBL1313774 0.84 CYP1A2 (0.39) CYP1A2SMN1; SMN2NAAAALDH1A1TDP1
SCHEMBL27904648 0.84 CYP1A2 (0.39) CYP1A2SMN1; SMN2NAAAALDH1A1TDP1
SCHEMBL1131415 0.82 CYP1A2 (0.40) CYP1A2SMN1; SMN2NAAATSHRCNR2
SCHEMBL1313844 0.82 CYP1A2 (0.40) CYP1A2SMN1; SMN2NAAAALDH1A1TSHR
SCHEMBL907210 0.82 CYP1A2 (0.40) CYP1A2SMN1; SMN2NAAAALDH1A1TSHR
SCHEMBL27668569 0.82 SMN1; SMN2 (0.39) CYP1A2SMN1; SMN2NAAAALDH1A1TDP1
SCHEMBL2496204 0.79 CYP1A2 (0.37) CYP1A2SMN1; SMN2NAAAALDH1A1TDP1
SCHEMBL2493181 0.79 CYP1A2 (0.37) CYP1A2SMN1; SMN2NAAAALDH1A1TDP1
SCHEMBL2494452 0.79 CYP1A2 (0.37) CYP1A2SMN1; SMN2NAAAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163950-B2 Processes for the production of tri-organo-monoalkoxysilanes and process for the production of tri-organo-monochlorosilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-24 US disclosed
US-20110275849-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES BANNOU TADASHI 2011-11-10 US disclosed
US-8008521-B2 Processes for the production of tri-organo-monoalkoxysilanes and process for the production of tri-organo-monochlorosilanes HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2011-08-30 US disclosed
US-20090082585-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES BANNOU TADASHI 2009-03-26 US disclosed
US-7459577-B2 Reacting a chlorosilane with grignard reagent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US disclosed
US-20050070730-A1 Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275849-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES MLX, HAX1, RPS4X CYP1A2 198/4885SMN1; SMN2 4285/4885NAAA 3898/4885
US-20090082585-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES MLX, HAX1, RPS4X CYP1A2 198/4885SMN1; SMN2 4285/4885NAAA 3898/4885
US-20050070730-A1 Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes MLX, HAX1, GRIA3 CYP1A2 255/4885SMN1; SMN2 3661/4885NAAA 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.