SCHEMBL1315041

SCHEMBL1315041

CNC(=O)N(C)c1cccc(N(C)C(=O)NC)c1C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.37
GAA P10253 4/20 0.35
ALDH1A1 P00352 3/20 0.35
TSHR P16473 3/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TSPO P30536 1/20 0.35
HSD17B1 P14061 3/20 0.35
HSD17B2 P37059 3/20 0.35
CYP3A4 P08684 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 2/20 0.34
GLA P06280 1/20 0.34
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16267030 0.84 GAA (0.48) ROCK2GAAALDH1A1TSHRTP53
SCHEMBL31442198 0.82 SIGMAR1 (0.45) ALDH1A1TP53HSD17B1HSD17B2LMNA
SCHEMBL5814272 0.82 SIGMAR1 (0.45) ALDH1A1TP53HSD17B1HSD17B2LMNA
SCHEMBL9020790 0.82 SCN4A (0.37) ROCK2GAAALDH1A1TP53MAPT
SCHEMBL10562347 0.80 HSD17B1 (0.34) ROCK2GAAALDH1A1TP53MAPT
SCHEMBL5049141 0.80 CXCR2 (0.41) ROCK2GAAALDH1A1TSHRTP53
SCHEMBL1624391 0.78 KDM4E (0.40) GAAALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL28851168 0.78 SIGMAR1 (0.61) GAAALDH1A1NPC1RAB9ASIGMAR1
SCHEMBL29809831 0.78 KDM4E (0.40) GAAALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL28986106 0.77 GAA (0.43) GAAALDH1A1TSHRTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752739-B2 Particulate curing components HEXCEL COMPOSITES LIMITED (GB) 2020-08-25 US claimed
US-20190144615-A1 PARTICULATE CURING COMPONENTS HEXCEL COMPOSITES LIMITED (GB) 2019-05-16 US claimed
US-5587236-A VEHICLE ACCESSSORIES AFFIXED TO VEHICULAR WINDSHIELD; HIGH BOND STRENGTH DONNELLY CORPORATION (US) 1996-12-24 US claimed
EP-3302944-B1 PROCESS FOR PREPARING MOULDED ARTICLES FROM FIBRE-REINFORCED COMPOSITE MATERIALS AND PREPREG OF FIBRE REINFORCED CURABLE COMPOSITE MATERIAL CYTEC IND INC (US) 2021-04-14 EP disclosed
US-10780608-B2 Process for preparing moulded articles from fibre-reinforced composite materials—II CYTEC INDUSTRIES INC. (US) 2020-09-22 US disclosed
EP-3302945-B1 AUTOMATED PROCESS FOR CONVEYING PREPREGS WITH THE PREPREG COMPRISING A DRY-FIBRE VEIL SURFACE LAYER AND PREPREG CYTEC IND INC (US) 2020-08-05 EP disclosed
EP-3302944-A1 PROCESS FOR PREPARING MOULDED ARTICLES FROM FIBRE-REINFORCED COMPOSITE MATERIALS AND PREPREG OF FIBRE REINFORCED CURABLE COMPOSITE MATERIAL Cytec Industries Inc. (US) 2018-04-11 EP disclosed
EP-3302945-A1 AUTOMATED PROCESS FOR CONVEYING PREPREGS WITH THE PREPREG COMPRISING A DRY-FIBRE VEIL SURFACE LAYER AND PREPREG Cytec Industries Inc. (US) 2018-04-11 EP disclosed
US-9926418-B2 Curative fibre components CYTEC INDUSTRIAL MATERIALS (DERBY) LIMITED (GB) 2018-03-27 US disclosed
US-20160346958-A1 Process for Preparing Moulded Articles from Fibre-Reinforced Composite Materials - I CYTEC INDUSTRIES INC. (US) 2016-12-01 US disclosed
US-20160346959-A1 Process for Preparing Moulded Articles from Fibre-Reinforced Composite Materials - II CYTEC INDUSTRIES INC. (US) 2016-12-01 US disclosed
US-8883305-B2 Thermoset resin fibres Umeco Structual Materials (Derby) Limited (GB) 2014-11-11 US disclosed
US-20120128976-A1 THERMOSET RESIN FIBRES ADVANCED COMPOSITES GROUP LIMITED (GB) 2012-05-24 US disclosed
US-8084126-B2 Thermoset resin fibres ADVANCED COMPOSITES GROUP LIMITED (GB) 2011-12-27 US disclosed
US-20110274907-A1 CURATIVE FIBRE COMPONENTS ADVANCED COMPOSITES GROUP LIMITED 2011-11-10 US disclosed
US-20100203787-A1 THERMOSET RESIN FIBRES ADVANCED COMPOSITES GROUP LIMITED (GB) 2010-08-12 US disclosed
EP-0091401-B1 PROCESS FOR PREPARING PREPREGS FROM FIBRES THAT CONTAIN CELLULOSE USING AQUEOUS RESIN COMPOSITIONS CIBA-GEIGY AG (CH) 1986-11-20 EP disclosed
US-4440802-A Preparation of prepregs from cellulosic fibers using water-borne resin compositions CIBA-GEIGY CORPORATION (US) 1984-04-03 US disclosed
EP-0091401-A2 Process for preparing prepregs from fibres that contain cellulose using aqueous resin compositions CIBA-GEIGY AG (CH) 1983-10-12 EP disclosed