SCHEMBL13151909

SCHEMBL13151909

COc1cc(/N=N/c2cccc(P(=O)(O)O)c2)ccc1Nc1nc(O)nc(Nc2ccc(/N=N/c3cc(S(=O)(=O)O)c4cc(S(=O)(=O)O)ccc4c3)c(C)c2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 11/20 0.49
▸ PTPRC P08575 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ PTPN6 P29350 1/20 0.37
▸ PTPN7 P35236 1/20 0.37
▸ PTPN11 Q06124 1/20 0.37
▸ PTPRJ Q12913 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ DUSP26 Q9BV47 1/20 0.37
▸ MEN1 O00255 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ CHAT P28329 1/20 0.35
▸ FUT8 Q9BYC5 1/20 0.34
▸ ATIC P31939 1/20 0.34
▸ SUMO2 P61956 1/20 0.34
▸ SUMO1 P63165 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13151899 0.94 ENPP2 (0.52) ENPP2MEN1THRBKMT2AALDH1A1
SCHEMBL13151869 0.93 ENPP2 (0.49) ENPP2PTPRCALOX15PTPN1PTPN6
SCHEMBL13879847 0.92 ENPP2 (0.51) ENPP2MEN1THRBKMT2AALDH1A1
SCHEMBL13151865 0.88 ENPP2 (0.57) ENPP2PTPRCALOX15PTPN1PTPN6
SCHEMBL13151859 0.86 ENPP2 (0.47) ENPP2PTPRCALOX15PTPN1PTPN6
SCHEMBL13152010 0.82 ENPP2 (0.56) ENPP2PTPRCALOX15PTPN1PTPN6
SCHEMBL13151976 0.82 ENPP2 (0.46) ENPP2MEN1KMT2AALDH1A1HIF1A
SCHEMBL13151936 0.80 ENPP2 (0.47) ENPP2MEN1THRBKMT2ACHAT
SCHEMBL13151826 0.79 GAA (0.39) MEN1KMT2AALDH1A1
SCHEMBL13388972 0.78 ENPP2 (0.55) ENPP2PTPRCALOX15PTPN1PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799122-B2 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-09-21 — — US disclosed
US-7799122-B2 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-09-21 — — US disclosed
US-20100151212-A1 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-06-17 — — US disclosed
US-20100151212-A1 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-06-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100151212-A1 Azo compounds PAH, CYP1A1, RB1 ENPP2 3818/4885PTPRC 1783/4885ALOX15 3606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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