SCHEMBL13151859

SCHEMBL13151859

COc1cc(/N=N/c2cccc(S(=O)(=O)O)c2)ccc1Nc1nc(O)nc(Nc2ccc(/N=N/c3cc(S(=O)(=O)O)c4cccc(S(=O)(=O)O)c4c3)c(C)c2)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 7/20 0.47
▸ SENP2 Q9HC62 4/20 0.47
▸ ATIC P31939 2/20 0.47
▸ SUMO2 P61956 2/20 0.47
▸ SUMO1 P63165 2/20 0.47
▸ SENP7 Q9BQF6 2/20 0.47
▸ MEN1 O00255 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ FUT8 Q9BYC5 1/20 0.36
▸ CHAT P28329 1/20 0.35
▸ SENP3 Q9H4L4 3/20 0.35
▸ SENP1 Q9P0U3 3/20 0.35
▸ PTPRC P08575 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ PTPN6 P29350 1/20 0.34
▸ PTPN7 P35236 1/20 0.34
▸ PTPN11 Q06124 1/20 0.34
▸ PTPRJ Q12913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13151936 0.94 ENPP2 (0.47) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL13151869 0.92 ENPP2 (0.49) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL13151865 0.91 ENPP2 (0.57) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL13151900 0.91 SENP2 (0.40) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL13151899 0.88 ENPP2 (0.52) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL13151875 0.88 ATIC (0.51) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL13151976 0.86 ENPP2 (0.46) ENPP2MEN1KMT2AFUT8CHAT
SCHEMBL13151909 0.86 ENPP2 (0.49) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL12558914 0.86 SENP2 (0.62) ENPP2SENP2ATICSUMO2SUMO1
SCHEMBL13879847 0.85 ENPP2 (0.51) ENPP2SENP2ATICSUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799122-B2 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-09-21 — — US disclosed
US-7799122-B2 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-09-21 — — US disclosed
US-20100151212-A1 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-06-17 — — US disclosed
US-20100151212-A1 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-06-17 — — US disclosed
EP-1913091-B1 AZO COMPOUNDS FUJIFILM IMAGING COLORANTS LTD (GB) 2009-04-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100151212-A1 Azo compounds PAH, CYP1A1, RB1 ENPP2 3818/4885SENP2 4536/4885ATIC 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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