Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMM2 | O15305 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | MPI | P34949 | 2/20 | 0.46 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10254740 | 0.85 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13460259 | 0.84 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13152691 | 0.84 | KDM1A (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13152592 | 0.83 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10095343 | 0.80 | KDM4E (0.52) | ALDH1A1 | |
| SCHEMBL13153385 | 0.79 | HTT (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14176085 | 0.76 | SSTR5 (0.49) | ALDH1A1 | |
| SCHEMBL13152675 | 0.74 | CTSL (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28854556 | 0.72 | ALDH1A1 (0.46) | PMM2MIFMPIPHOSPHO1NPC1 | |
| SCHEMBL13152103 | 0.71 | MAPK8 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |