SCHEMBL13152161

SCHEMBL13152161

COc1ccc(N(c2ccc(Cl)cc2)c2ccc(-c3ccc(-c4ccc(N(c5ccc(Cl)cc5)c5ccc(OC)cc5C)cc4)cc3)cc2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ALOX12 P18054 3/20 0.38
NPSR1 Q6W5P4 3/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CNR1 P21554 1/20 0.38
CYP2C19 P33261 1/20 0.38
CNR2 P34972 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
GPBAR1 Q8TDU6 1/20 0.38
ALOX15 P16050 2/20 0.37
TP53 P04637 2/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13152156 0.89 NPC1 (0.39) MAPTKDM4ETP53HPGDGAA
SCHEMBL13236076 0.89 BCL2A1 (0.38) MEN1KMT2AALOX12NPSR1MAPT
SCHEMBL29511979 0.86 MEN1 (0.43) MEN1KMT2AMAPTCYP1A2TDP1
SCHEMBL13152130 0.86 CYP11B1 (0.43) MEN1KMT2ANPSR1KDM4ECYP1A2
SCHEMBL1673428 0.86 MEN1 (0.43) MEN1KMT2AMAPTCYP1A2TDP1
SCHEMBL2734807 0.86 MEN1 (0.43) MEN1KMT2AMAPTCYP1A2TDP1
SCHEMBL8944108 0.85 CA1 (0.42) CYP1A2GAACA1CA2
SCHEMBL10057771 0.83 DYRK1A (0.44) MAPTKDM4ETP53HPGDLMNA
SCHEMBL13152131 0.82 CA12 (0.40) MEN1KMT2AMAPTKDM4ECYP1A2
SCHEMBL12463495 0.82 KMT2A (0.40) MEN1KMT2ANPSR1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799492-B2 P-terphenyl compound and photosensitive body for electrophotography using such compound HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-21 US disclosed
US-7799492-B2 P-terphenyl compound and photosensitive body for electrophotography using such compound HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-21 US disclosed
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-03-27 US disclosed
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound SLCO2A1, SLCO2B1, SLC26A4 MEN1 2956/4885KMT2A 3127/4885ALOX12 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.