Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 3/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12109159 | 0.89 | GRIK2 (0.39) | GRIK2GRIK1KDM4EALDH1A1MAPK1 | |
| SCHEMBL10252659 | 0.86 | GRIK2 (0.54) | GRIK2GRIK1KDM4EALDH1A1MAPK1 | |
| SCHEMBL10095918 | 0.85 | GRIK2 (0.39) | GRIK2GRIK1RORCKDM4EALDH1A1 | |
| SCHEMBL13152314 | 0.84 | ALDH1A1 (0.41) | RORCKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL13152272 | 0.81 | GRIK2 (0.39) | GRIK2GRIK1KDM4EALDH1A1MAPK1 | |
| SCHEMBL10249495 | 0.81 | KMT2A (0.46) | RORCKDM4EALDH1A1MAPK1HTT | |
| SCHEMBL13152405 | 0.81 | HPGD (0.42) | RORCKDM4EALDH1A1MAPK1HTT | |
| SCHEMBL10254357 | 0.81 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPK1HTTHSD17B10 | |
| SCHEMBL13152111 | 0.81 | GRIK2 (0.38) | GRIK2GRIK1KDM4EALDH1A1MAPK1 | |
| SCHEMBL13151837 | 0.81 | GRIK2 (0.41) | GRIK2GRIK1KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |