Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152631 | 0.96 | MEN1 (0.33) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL13151796 | 0.88 | NPC1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL13152786 | 0.87 | MEN1 (0.34) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL13152825 | 0.87 | MAPT (0.36) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL10096088 | 0.86 | MEN1 (0.35) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL12923561 | 0.85 | MAPT (0.38) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL10096096 | 0.85 | AAK1 (0.36) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL10096074 | 0.85 | RAB9A (0.40) | MEN1KMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL13152787 | 0.85 | HTR3A (0.32) | — | |
| SCHEMBL12995207 | 0.84 | NPSR1 (0.40) | MEN1KMT2AMAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |