SCHEMBL13154792

SCHEMBL13154792

Cc1cc(-c2nc(-c3cccc(-c4ccccn4)n3)nc(-c3cccc(-c4ccccn4)n3)n2)ccc1-c1cc2ccccc2c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
TP53 P04637 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
MAPK1 P28482 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
ALPL P05186 1/20 0.42
HSP90AA1 P07900 1/20 0.42
ALPI P09923 1/20 0.42
ALPG P10696 1/20 0.42
ALOX15 P16050 1/20 0.42
HTT P42858 1/20 0.42
ADORA3 P0DMS8 8/20 0.39
NPC1 O15118 4/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3294308 0.89 CA12 (0.46) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL13154435 0.86 KDM4E (0.50) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL3295246 0.85 CYP11B1 (0.41) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL13389113 0.85 KDM4E (0.49) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL13154791 0.84 CCR1 (0.42) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL13154576 0.83 KDM4E (0.45) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL3299769 0.83 NPC1 (0.50) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL13154457 0.82 KDM4E (0.55) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL13154777 0.82 KDM4E (0.45) KDM4ETP53TDP1MAPK1SMN1; SMN2
SCHEMBL13154790 0.81 NPC1 (0.44) KDM4ETP53TDP1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2236506-A1 Compound having triazine ring structure substituted with group and organic electroluminescent device Hodogaya Chemical Co., Ltd. (JP) 2010-10-06 EP disclosed
US-20100090588-A1 COMPOUND HAVING TRIAZINE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-04-15 US disclosed
US-20100090588-A1 COMPOUND HAVING TRIAZINE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-04-15 US disclosed
EP-2055704-A1 COMPOUND HAVING TRIAZINE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2009-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100090588-A1 COMPOUND HAVING TRIAZINE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE SCO2, OR51E2, NONO KDM4E 756/4885TP53 3307/4885TDP1 2408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.