SCHEMBL3294308

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3299769	0.94	NPC1 (0.50)	CA12CA1CA2CA9NPC1
	SCHEMBL13154792	0.89	KDM4E (0.42)	CA12CA1CA2CA9NPC1
	SCHEMBL3295246	0.89	CYP11B1 (0.41)	CA12CA1CA2CA9NPC1
	SCHEMBL13154370	0.88	KDM4E (0.49)	CA12CA1CA2CA9NPC1
	SCHEMBL13154435	0.87	KDM4E (0.50)	NPC1KDM4ESMN1; SMN2TP53MAPT
	SCHEMBL13154791	0.87	CCR1 (0.42)	NPC1KDM4ESMN1; SMN2TP53MAPT
	SCHEMBL10068442	0.84	CA12 (0.59)	CA12CA1CA2CA9KDM4E
	SCHEMBL13154576	0.84	KDM4E (0.45)	NPC1KDM4ESMN1; SMN2TP53MAPT
	SCHEMBL13154454	0.83	KDM4E (0.51)	CA12CA1CA2CA9NPC1
	SCHEMBL13154777	0.83	KDM4E (0.45)	NPC1KDM4ESMN1; SMN2TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.