Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341860 | 1.00 | HSD17B10 (0.36) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL16473876 | 0.88 | HSD17B10 (0.44) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL13155260 | 0.88 | LPAR1 (0.32) | LPAR1LPAR3 | |
| SCHEMBL23408864 | 0.86 | HSD17B10 (0.46) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL20089588 | 0.82 | HSD17B10 (0.40) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL2624359 | 0.80 | LPAR1 (0.42) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL12410368 | 0.80 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616848 | 0.80 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616857 | 0.80 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL20026178 | 0.79 | USP2 (0.32) | USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7794700-B2 | Multimeric VLA-4 antagonists comprising polymer moieties | ELAN PHARMACEUTICALS INC. (US) | 2010-09-14 | — | — | US | disclosed |