Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16473876 | 0.94 | HSD17B10 (0.44) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL23408864 | 0.91 | HSD17B10 (0.46) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL9657338 | 0.89 | LPAR1 (0.39) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616845 | 0.87 | HSD17B10 (0.43) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| Ether SCHEMBL11844631 | 0.85 | HSD17B10 (0.44) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616857 | 0.84 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616848 | 0.84 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL12410368 | 0.84 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL18281575 | 0.83 | LPAR1 (0.38) | LPAR1LPAR3LPAR2ALDH1A1TSHR | |
| SCHEMBL14616851 | 0.83 | HSD17B10 (0.40) | HSD17B10TDP1LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | OPRL1, OGFR, F12 | HSD17B10 1937/4885TDP1 4303/4885LPAR1 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.