SCHEMBL13156129

SCHEMBL13156129

Cc1ccc2c(c1)[N+](Cc1ccccc1)=C(C=CC=CN(C)C)C2(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.37
INSR P06213 1/20 0.34
MAPT P10636 4/20 0.33
LMNA P02545 3/20 0.33
MEN1 O00255 2/20 0.33
THRB P10828 2/20 0.33
HTT P42858 2/20 0.33
RECQL P46063 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
USP2 O75604 1/20 0.33
S1PR2 O95136 1/20 0.33
POLB P06746 1/20 0.33
ALPG P10696 1/20 0.33
PKM P14618 1/20 0.33
XBP1 P17861 1/20 0.33
CRHBP P24387 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13156133 0.78 MAPT (0.42) PRMT1INSRMAPTLMNAMEN1
SCHEMBL13645482 0.73 MAPT (0.51) PRMT1MAPTLMNAMEN1THRB
SCHEMBL13645521 0.73 PRMT1 (0.39) PRMT1MAPTAPP
SCHEMBL12905408 0.71 APP (0.49) PRMT1INSRMAPTLMNAMEN1
SCHEMBL14723999 0.68 KMT2A (0.52) PRMT1MAPTLMNAMEN1THRB
SCHEMBL12905397 0.66 MAPT (0.56) INSRMAPTLMNAMEN1HTT
SCHEMBL2614406 0.65 MAPT (0.46) PRMT1MAPTLMNAMEN1THRB
SCHEMBL13645528 0.65 PRMT1 (0.39) PRMT1MAPTLMNAMEN1THRB
SCHEMBL1669108 0.65 MAPT (0.56) PRMT1MAPTLMNAMEN1THRB
SCHEMBL2614409 0.65 MAPT (0.45) PRMT1MAPTLMNAMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799927-B2 Indolestyryl compound and high density recording media utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-09-21 US disclosed
US-20070219377-A1 Indolestyryl compound and high density recording media utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219377-A1 Indolestyryl compound and high density recording media utilizing the same ASH2L, C1S, CBS PRMT1 33/4885INSR 255/4885MAPT 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.