Benzo[B]Phenazine

Benzo[B]Phenazine

SCHEMBL5481172

c1ccc2cc3nc4ccccc4nc3cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 6/20 1.00
MAPT P10636 4/20 0.69
ALDH1A1 P00352 4/20 0.63
HPGD P15428 2/20 0.63
GLA P06280 1/20 0.63
ACHE P22303 1/20 0.63
MEN1 O00255 2/20 0.62
NPC1 O15118 2/20 0.62
POLB P06746 2/20 0.62
KMT2A Q03164 2/20 0.62
USP2 O75604 1/20 0.62
CACNA1B Q00975 1/20 0.62
APBA1 Q02410 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
KDM4E B2RXH2 3/20 0.56
LMNA P02545 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31319857 0.97 NQO2 (0.94) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL13156494 0.94 NQO2 (0.89) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL13156487 0.94 NQO2 (0.88) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL5469928 0.88 MAPT (0.82) NQO2MAPTALDH1A1HPGDGLA
Benz(B)Anthracene SCHEMBL15569365 0.88 NQO2 (0.78) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL29614768 0.87 MAPT (0.79) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL4612924 0.87 MAPT (0.79) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL13156546 0.87 MAPT (0.79) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL13156491 0.85 MAPT (0.78) NQO2MAPTALDH1A1HPGDGLA
Phenazine SCHEMBL28246698 0.83 MAPT (0.85) NQO2MAPTALDH1A1HPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12377173-B2 Compositions comprising hyperpolarized probes for H2O2 sensing and methods of using same DUKE UNIVERSITY (US) 2025-08-05 US disclosed
US-20220378952-A1 COMPOSITIONS COMPRISING HYPERPOLARIZED PROBES FOR H2O2 SENSING AND METHODS OF USING SAME DUKE UNIVERSITY 2022-12-01 US disclosed
US-20220146606-A1 POLARIZATION SOURCE FOR DYNAMIC NUCLEAR POLARIZATION, COMPOSITION, COMPOSITION FOR DYNAMIC NUCLEAR POLARIZATION, METHOD FOR HYPERPOLARIZATION, HYPERPOLARIZED SUBSTANCE AND NMR MEASUREMENT METHOD KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-05-12 US disclosed
US-20220146606-A1 POLARIZATION SOURCE FOR DYNAMIC NUCLEAR POLARIZATION, COMPOSITION, COMPOSITION FOR DYNAMIC NUCLEAR POLARIZATION, METHOD FOR HYPERPOLARIZATION, HYPERPOLARIZED SUBSTANCE AND NMR MEASUREMENT METHOD KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-05-12 US disclosed
EP-3932911-A1 POLARIZATION SOURCE FOR DYNAMIC NUCLEAR POLARIZATION, COMPOSITION, COMPOSITION FOR DYNAMIC NUCLEAR POLARIZATION, METHOD FOR HYPERPOLARIZATION, HYPERPOLARIZED SUBSTANCE AND NMR MEASUREMENT METHOD Kyushu University, National University Corporation (JP) 2022-01-05 EP disclosed
EP-3932911-A1 POLARIZATION SOURCE FOR DYNAMIC NUCLEAR POLARIZATION, COMPOSITION, COMPOSITION FOR DYNAMIC NUCLEAR POLARIZATION, METHOD FOR HYPERPOLARIZATION, HYPERPOLARIZED SUBSTANCE AND NMR MEASUREMENT METHOD Kyushu University, National University Corporation (JP) 2022-01-05 EP disclosed
CN-106518894-A Ag(I) coordination compound with dichloromethane fluorescence enhancement effect, preparing method and application 盐城工学院 2017-03-22 CN disclosed
US-7800103-B2 Organic thin film transistor material, organic thin film transistor, field-effect transistor, switching element, organic semiconductor material and organic semiconductor film KONICA MINOLTA HOLDINGS, INC. (JP) 2010-09-21 US disclosed
US-7800103-B2 Organic thin film transistor material, organic thin film transistor, field-effect transistor, switching element, organic semiconductor material and organic semiconductor film KONICA MINOLTA HOLDINGS, INC. (JP) 2010-09-21 US disclosed
WO-2008120839-A1 NOVEL ORGANIC SEMICONDUCTOR COMPOUND, AND ORGANIC THIN FILM TRANSISTOR USING THE SAME GYEONGSANG NATIONAL UNIVERSITY INDUSTRIAL AND ACADEMIC COLLABORATION FOUNDATION (KR) 2008-10-09 WO disclosed
US-20080121873-A1 Organic Thin Film Transistor Material, Organic Thin Film Transistor, Field-Effect Transistor, Switching Element, Organic Semiconductor Material and Organic Semiconductor Film KONICA MINOLTA HOLDINGS, INC. (JP) 2008-05-29 US disclosed
US-20080121873-A1 Organic Thin Film Transistor Material, Organic Thin Film Transistor, Field-Effect Transistor, Switching Element, Organic Semiconductor Material and Organic Semiconductor Film KONICA MINOLTA HOLDINGS, INC. (JP) 2008-05-29 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146606-A1 POLARIZATION SOURCE FOR DYNAMIC NUCLEAR POLARIZATION, COMPOSITION, COMPOSITION FOR DYNAMIC NUCLEAR POLARIZATION, METHOD FOR HYPERPOLARIZATION, HYPERPOLARIZED SUBSTANCE AND NMR MEASUREMENT METHOD H1-10, ZYX, HNRNPR NQO2 1580/4885MAPT 2217/4885ALDH1A1 4418/4885
US-12377173-B2 Compositions comprising hyperpolarized probes for H2O2 sensing and methods of using same BRI3BP, GPX4, PRDX5 NQO2 201/4885MAPT 4491/4885ALDH1A1 4371/4885
US-20080121873-A1 Organic Thin Film Transistor Material, Organic Thin Film Transistor, Field-Effect Transistor, Switching Element, Organic Semiconductor Material and Organic Semiconductor Film TERT, TELO2, RCOR1 NQO2 2650/4885MAPT 433/4885ALDH1A1 2953/4885
US-20220378952-A1 COMPOSITIONS COMPRISING HYPERPOLARIZED PROBES FOR H2O2 SENSING AND METHODS OF USING SAME BRI3BP, GPX4, PRDX5 NQO2 201/4885MAPT 4491/4885ALDH1A1 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.