Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19720320 | 0.93 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL2820157 | 0.89 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL13108359 | 0.87 | L3MBTL1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL3101531 | 0.87 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL13157394 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL2822158 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL2822832 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL2820214 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL3833133 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL2823151 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749554-A2 | 2,5-disubstituted arylsulfonamide CCR3 antagonists | Axikin Pharmaceuticals, Inc. (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2010123959-A2 | 2,5-DISUBSTITUTED ARYLSULFONAMIDE CCR3 ANTAGONISTS | AXIKIN PHARMACEUTICALS, INC. (US) | 2010-10-28 | — | — | WO | disclosed |