Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61425 | 0.86 | NOTUM (0.58) | NOTUMMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16285249 | 0.86 | HRH3 (0.52) | ALDH1A1MAPTHRH3CA12CA2 | |
| Ethane SCHEMBL8133601 | 0.77 | NOTUM (0.51) | NOTUMMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28295817 | 0.77 | MAPT (0.52) | MEN1ALDH1A1MAPTKMT2AUSP2 | |
| SCHEMBL26798770 | 0.76 | AR (0.46) | NOTUMALDH1A1MAPTHRH3HSD11B1 | |
| SCHEMBL1410143 | 0.76 | NOTUM (0.63) | NOTUMMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL169776 | 0.76 | ADRB1 (0.53) | MEN1ALDH1A1MAPTKMT2AUSP2 | |
| SCHEMBL5538409 | 0.76 | NOTUM (0.54) | NOTUMALDH1A1MAPTHRH3CA12 | |
| SCHEMBL1244796 | 0.75 | FFAR4 (0.50) | NOTUM | |
| Hydrochloric Acid SCHEMBL27929442 | 0.74 | NOTUM (0.53) | NOTUMALDH1A1MAPTHRH3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115688-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-10-14 | — | — | WO | disclosed |