Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LGMN | Q99538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270272 | 0.84 | MAPT (0.65) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL2203983 | 0.84 | AKR1C3 (0.68) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL16000561 | 0.82 | MAPT (0.63) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL14614585 | 0.81 | MAPT (0.52) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL5738297 | 0.81 | MAPT (0.54) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL9093746 | 0.78 | LMNA (0.71) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL24921231 | 0.78 | NPC1 (0.54) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL8375217 | 0.78 | MAPT (0.49) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL13930909 | 0.78 | MAPT (0.49) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL26357634 | 0.78 | MAPT (0.51) | MAPTALDH1A1KDM4EMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704914-A | A kind of facile syntheesis new method of 1,1- bis-fluoro ethyls aromatic compound | 山东理工大学 | 2019-05-03 | — | — | CN | disclosed |