Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMURF1 | Q9HCE7 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13158458 | 0.91 | PTGS2 (0.52) | HPGDMAPTPTGS2TP53SMURF1 | |
| SCHEMBL13158460 | 0.90 | RAB9A (0.53) | HPGDMAPTPTGS2TP53SMURF1 | |
| SCHEMBL13158446 | 0.89 | PTGS2 (0.46) | MAPTPTGS2TP53CA2CA1 | |
| SCHEMBL13158427 | 0.87 | PTGS2 (0.49) | HPGDMAPTPTGS2TP53SMURF1 | |
| SCHEMBL13158457 | 0.86 | MAPK14 (0.48) | MAPTPTGS2TP53CA2CA1 | |
| SCHEMBL13158482 | 0.85 | PTGS2 (0.49) | HPGDMAPTPTGS2TP53SMURF1 | |
| SCHEMBL3105762 | 0.84 | PTGS2 (0.46) | HPGDMAPTPTGS2TP53SMURF1 | |
| SCHEMBL13158456 | 0.84 | PTGS2 (0.46) | HPGDMAPTPTGS2TP53SMURF1 | |
| SCHEMBL3112232 | 0.84 | RXFP1 (0.43) | HPGDMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13158440 | 0.84 | MAPK14 (0.52) | HPGDMAPTPTGS2TP53SMURF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803822-B2 | Triazole derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090105253-A1 | Triazole Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105253-A1 | Triazole Derivative and Use Thereof | F2R, HRH4, F2RL3 | HPGD 800/4885MAPT 4724/4885GRM1 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.