Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077519 | 0.84 | NAMPT (0.56) | TP53HSD17B10HDAC1HDAC6KDM4E | |
| SCHEMBL3401575 | 0.81 | AKR1C3 (0.53) | TP53AKR1C3ALDH1A1HPGDTSHR | |
| SCHEMBL13159280 | 0.79 | HPGD (0.69) | TP53AKR1C3ALDH1A1HPGDTSHR | |
| SCHEMBL11146062 | 0.78 | KDM4E (0.55) | TP53HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11974237 | 0.78 | HPGD (0.61) | TP53HSD17B10HDAC1HDAC6KDM4E | |
| SCHEMBL27938990 | 0.76 | MLYCD (0.67) | HSD17B10HDAC1HDAC6KDM4EALDH1A1 | |
| SCHEMBL13159354 | 0.75 | TDP1 (0.42) | TP53AKR1C3ALDH1A1GAA | |
| SCHEMBL11188824 | 0.75 | AKR1C3 (0.50) | TP53AKR1C3ALDH1A1HPGDTSHR | |
| SCHEMBL3309083 | 0.74 | AKR1C3 (0.53) | AKR1C3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL20537075 | 0.74 | LIG1 (0.58) | AKR1C3HSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222454-A1 | DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT | CIBA CORPORATION (US) | 2010-09-02 | — | — | US | disclosed |