SCHEMBL3401575

SCHEMBL3401575

O=C(c1ccccc1)c1ccccc1C(=O)N(CCO)CCO

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.53
TP53 P04637 1/20 0.53
GAA P10253 2/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 4/20 0.45
HPGD P15428 1/20 0.45
CDC25B P30305 1/20 0.43
ATM Q13315 1/20 0.43
NR4A1 P22736 1/20 0.42
TSHR P16473 2/20 0.42
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4089780 0.87 TP53 (0.67) TP53MAPTALDH1A1TSHRTRPV1
SCHEMBL21561693 0.84 TP53 (0.58) AKR1C3TP53MAPTALDH1A1HPGD
SCHEMBL11208187 0.83 AKR1C3 (0.50) AKR1C3TP53GAAMAPTALDH1A1
SCHEMBL13159354 0.83 TDP1 (0.42) AKR1C3TP53GAAALDH1A1CDC25B
SCHEMBL154607 0.81 HPGD (0.53) TP53GAAMAPTALDH1A1HPGD
SCHEMBL13159486 0.81 TP53 (0.51) AKR1C3TP53GAAMAPTALDH1A1
SCHEMBL13159280 0.81 HPGD (0.69) AKR1C3TP53GAAMAPTALDH1A1
SCHEMBL25828187 0.80 POLB (0.57) TP53GAAMAPTALDH1A1
Hydrochloric Acid SCHEMBL27871652 0.80 HPGD (0.52) TP53GAAMAPTALDH1A1HPGD
SCHEMBL12643814 0.79 ELANE (0.39) AKR1C3TP53GAAALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708425-B2 Routes to polyacrylates COLOPLAST A/S (DK) 2017-07-18 US claimed
US-9371308-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2016-06-21 US claimed
EP-2638078-B1 NEW ROUTES TO POLYACRYLATES COLOPLAST AS (DK) 2015-01-07 EP claimed
EP-2638077-B1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST AS (DK) 2015-01-07 EP claimed
US-20130296454-A1 ROUTES TO POLYACRYLATES COLOPLAST A/S (DK) 2013-11-07 US claimed
US-20130289155-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2013-10-31 US claimed
EP-4249518-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-27 EP disclosed
EP-2850111-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP disclosed
US-9708425-B2 Routes to polyacrylates COLOPLAST A/S (DK) 2017-07-18 US disclosed
US-9670373-B2 Polymers comprising photoinitiator moieties and dye moieties LAMBSON LIMITED (GB) 2017-06-06 US disclosed
US-9371308-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2016-06-21 US disclosed
US-9296835-B2 Polymeric photoinitiators and photoinitiator monomers COLOPLAST A/S (DK) 2016-03-29 US disclosed
US-20150148441-A1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST A/S (DK) 2015-05-28 US disclosed
US-20130296454-A1 ROUTES TO POLYACRYLATES COLOPLAST A/S (DK) 2013-11-07 US disclosed
US-20130289155-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2013-10-31 US disclosed
US-20100222454-A1 DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT CIBA CORPORATION (US) 2010-09-02 US disclosed
US-20100222454-A1 DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT CIBA CORPORATION (US) 2010-09-02 US disclosed
US-20100222454-A1 DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT CIBA CORPORATION (US) 2010-09-02 US disclosed
EP-2176210-A1 DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT BASF SE (DE) 2010-04-21 EP disclosed
WO-2009016083-A1 DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT BASF SE (CH) 2009-02-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148441-A1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS PPOX, ALAD, AAAS AKR1C3 973/4885TP53 1958/4885GAA 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.