Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924700 | 0.80 | LTA4H (0.48) | LMNATP53GAARAB9ANPC1 | |
| SCHEMBL11111613 | 0.79 | LTA4H (0.53) | TP53MAPTLTA4HNR5A1TSHR | |
| SCHEMBL16435786 | 0.78 | NR5A1 (0.58) | LMNATP53GAARAB9ANPC1 | |
| SCHEMBL10034262 | 0.77 | LTA4H (0.47) | TP53LTA4HNR5A1TSHRPLA2G4B | |
| SCHEMBL10034261 | 0.77 | LTA4H (0.47) | TP53LTA4HNR5A1TSHRPLA2G4B | |
| SCHEMBL9907228 | 0.75 | TSHR (0.40) | LMNATP53GAARAB9ANPC1 | |
| SCHEMBL16437774 | 0.74 | RARB (0.55) | TP53LTA4HNR5A1TSHRPLA2G4B | |
| SCHEMBL3935979 | 0.74 | LTA4H (0.47) | LMNATP53GAARAB9ANPC1 | |
| SCHEMBL29390021 | 0.74 | NR5A1 (0.59) | LMNATP53GAARAB9ANPC1 | |
| SCHEMBL28942158 | 0.72 | LTA4H (0.66) | LMNATP53LTA4HNR5A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799573-B2 | Detection of explosives and other species | Normadics, Inc. (US) | 2010-09-21 | — | — | US | disclosed |
| US-20080248578-A1 | Detection of explosives and other species | NOMADICS, INC. (US) | 2008-10-09 | — | — | US | disclosed |