Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924700 | 0.88 | LTA4H (0.48) | LTA4HNR5A1TP53NPC1LMNA | |
| SCHEMBL28942158 | 0.80 | LTA4H (0.66) | LTA4HNR5A1TP53LMNACHRNB2 | |
| SCHEMBL10300046 | 0.80 | NR5A1 (0.66) | LTA4HNR5A1TP53NPC1LMNA | |
| SCHEMBL15559300 | 0.80 | NR5A1 (0.66) | LTA4HNR5A1TP53NPC1LMNA | |
| SCHEMBL28328005 | 0.78 | LTA4H (0.68) | LTA4HNR5A1TP53CHRNB2CHRNB4 | |
| SCHEMBL5710109 | 0.75 | NR5A1 (0.56) | LTA4HNR5A1TP53NPC1LMNA | |
| SCHEMBL29390021 | 0.75 | NR5A1 (0.59) | LTA4HNR5A1TP53NPC1LMNA | |
| SCHEMBL3923942 | 0.75 | MEN1 (0.42) | LTA4HTP53LMNAGAAMAPT | |
| SCHEMBL22911528 | 0.75 | LTA4H (0.48) | LTA4HNR5A1TP53CHRNB2CHRNB4 | |
| SCHEMBL28942149 | 0.75 | LTA4H (0.66) | LTA4HNR5A1TP53LMNACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313785-B1 | COMPOSITION COMPRISING IPTYCENE POLYMERS WITH HIGH INTERNAL VOLUME | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-04-01 | — | — | EP | disclosed |
| US-7494698-B2 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080188634-A1 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-08-07 | — | — | US | disclosed |
| US-20040170775-A1 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-09-02 | — | — | US | disclosed |
| US-6783814-B2 | GRAFT POLYMER OF POROUS POLYMER AND INTERPENETRATING POLYMER NETWORK | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-08-31 | — | — | US | disclosed |
| WO-2002016463-A9 | POLYMERS WITH HIGH INTERNAL FREE VOLUME | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-04-03 | — | — | WO | disclosed |
| US-20020150697-A1 | Polymers with high internal free volume | NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA | 2002-10-17 | — | — | US | disclosed |