Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267612 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL4257305 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL1012515 | 0.88 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL13163939 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL23882144 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7452382 | 0.87 | KDM4E (0.56) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL30710211 | 0.86 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL13162549 | 0.85 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL13162397 | 0.84 | HPGD (0.48) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL23757486 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | TRPV1, FGFR3, GPR17 | ALDH1A1 1659/4885KDM4E 1395/4885HSD17B10 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.