Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005829 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| SCHEMBL26037 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| SCHEMBL3099744 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| SCHEMBL8872842 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| SCHEMBL29575794 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| SCHEMBL2865 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| SCHEMBL23300518 | 0.66 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| Bromide SCHEMBL8065180 | 0.66 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| SCHEMBL10699512 | 0.66 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 | |
| Bromide SCHEMBL8065175 | 0.66 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10117860-B2 | Aminoester derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-11-06 | — | — | US | claimed |
| EP-3152201-B1 | AMINOESTER DERIVATIVES | CHIESI FARM SPA (IT) | 2018-08-29 | — | — | EP | claimed |
| US-20170340616-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-11-30 | — | — | US | claimed |
| US-20170226422-A1 | POLYMERISABLE MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | claimed |
| EP-3177695-A1 | POLYMERISABLE MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2017-06-14 | — | — | EP | claimed |
| EP-3152201-A1 | AMINOESTER DERIVATIVES | Chiesi Farmaceutici S.p.A. (IT) | 2017-04-12 | — | — | EP | claimed |
| WO-2015185649-A9 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-01-05 | — | — | WO | claimed |
| WO-2016020040-A1 | POLYMERISABLE MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-02-11 | — | — | WO | claimed |
| US-20150352091-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-12-10 | — | — | US | claimed |
| WO-2015185649-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-12-10 | — | — | WO | claimed |
| US-20110267574-A1 | LIQUID CRYSTAL DISPLAY DEVICE AND COMPOSITION FOR FORMING LIQUID CRYSTAL LAYER | SHARP KABUSHIKI KAISHA (JP) | 2011-11-03 | — | — | US | claimed |
| US-6946207-B2 | Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device | CANON KABUSHIKI KAISHA (JP) | 2005-09-20 | — | — | US | claimed |
| US-20020135292-A1 | Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device | CANON KABUSHIKI KAISHA (JP) | 2002-09-26 | — | — | US | claimed |
| US-5312707-A | Compositions for images | RICOH COMPANY, LTD. (JP) | 1994-05-17 | — | — | US | claimed |
| US-10472381-B2 | Sialic acid derivatives | REINHARD BROSSMER (DE) | 2019-11-12 | — | — | US | disclosed |
| EP-3083617-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-09-11 | — | — | EP | disclosed |
| EP-3157920-B1 | INDOLIZINE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-08-07 | — | — | EP | disclosed |
| US-5516577-A | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5312707-A | Compositions for images | RICOH COMPANY, LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0569827-A2 | Organic electroluminescence device | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472381-B2 | Sialic acid derivatives | NEU1, NEU2, NEU3 | ALDH1A1 127/4885HSD17B10 868/4885TSHR 693/4885 |
| US-20170340616-A1 | AMINOESTER DERIVATIVES | PDE4A, PDE4B, PDE3A | ALDH1A1 340/4885HSD17B10 437/4885TSHR 1080/4885 |
| US-20150352091-A1 | AMINOESTER DERIVATIVES | PDE4A, PDE4B, PDE3A | ALDH1A1 340/4885HSD17B10 437/4885TSHR 1080/4885 |
| US-10117860-B2 | Aminoester derivatives | PDE4A, PDE4B, PDE3A | ALDH1A1 340/4885HSD17B10 437/4885TSHR 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.