SCHEMBL2865

SCHEMBL2865

[C]1=Cc2cccc3cccc1c23

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 4/20 0.39
TSHR P16473 4/20 0.39
HPGD P15428 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
MAPK1 P28482 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
THRB P10828 1/20 0.32
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CES2 O00748 1/20 0.31
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31
MCL1 Q07820 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12520831 0.77 ALDH1A1 (0.36) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL1664200 0.77 ALDH1A1 (0.36) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL1005829 0.72 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL16817836 0.72 CYP1A2 (0.39) CYP1A2KDM4E
SCHEMBL110858 0.71
SCHEMBL7315832 0.70 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL16817767 0.69 TSHR (0.44) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL1316487 0.67 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL1663773 0.66 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL28125443 0.66 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17098 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043634-B2 Metal complexes, methods of making the same, and uses thereof THE UNIVERSITY OF MANITOBA (CA) 2024-07-23 US claimed
CN-118324771-A Organic light-emitting device, electronic device, and heterocyclic compound 三星显示有限公司 2024-07-12 CN claimed
CN-118324686-A Diazacyclo compound, cyclic trimethylcyanine compound, preparation methods thereof, imaging agent and application 南京大学 2024-07-12 CN claimed
EP-4392025-A1 ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS The Research Foundation for The State University of New York (US) 2024-07-03 EP claimed
CN-118271347-A Heterocyclic compound, organic light-emitting device including the same, and electronic device 三星显示有限公司 2024-07-02 CN claimed
CN-112054128-B Heterocyclic compound and organic light-emitting device comprising same 三星显示有限公司 2024-06-18 CN claimed
US-20240188315-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-06 US claimed
US-11999723-B2 Pyrazole-containing macrophage migration inhibitory factor inhibitors YALE UNIVERSITY (US) 2024-06-04 US claimed
US-12004417-B2 Heterocyclic compound and light-emitting device including same SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-04 US claimed
EP-3185328-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2024-05-22 EP claimed
EP-0078980-A1 Photosensitive composition and photosensitive copying material produced therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-18 EP claimed
US-4184871-A A,B-UNSATURATED NITRILE SENSITIZER MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1980-01-22 US claimed
US-4140681-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1979-02-20 US claimed
US-4131673-A INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1978-12-26 US claimed
US-4125604-A PEPTIDES, ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-11-14 US claimed
US-4101653-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4097472-A INHIBITION AND SUPRESSION OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-27 US claimed
US-4093712-A ANTITHROMBOGENIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-06 US claimed
US-4066773-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US claimed
US-3971804-A ACARICIDES, FUNGICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US claimed