Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165783 | 0.89 | CARM1 (0.40) | CARM1PRMT6FFAR1ACACB | |
| SCHEMBL13165799 | 0.82 | KLKB1 (0.45) | CARM1PRMT6ALDH1A1TP53L3MBTL1 | |
| SCHEMBL13166120 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TP53FFAR1L3MBTL1MEN1 | |
| SCHEMBL13165750 | 0.79 | FFAR1 (0.42) | ALDH1A1TP53FFAR1L3MBTL1PTPN7 | |
| SCHEMBL13165743 | 0.77 | ANPEP (0.53) | CARM1PRMT6ALDH1A1MEN1KMT2A | |
| SCHEMBL13165617 | 0.77 | ACACB (0.51) | CARM1PRMT6MEN1KMT2AACACB | |
| SCHEMBL10121390 | 0.76 | ALDH1A1 (0.43) | ALDH1A1FFAR1L3MBTL1POLBPTPN7 | |
| Trifluoroacetic Acid SCHEMBL2789683 | 0.76 | CARM1 (0.45) | CARM1PRMT6FFAR1L3MBTL1 | |
| SCHEMBL13165753 | 0.76 | CA12 (0.54) | ALDH1A1POLB | |
| SCHEMBL13165754 | 0.75 | PSMB5 (0.46) | CARM1PRMT6ALDH1A1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |