Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2788517 | 0.91 | CARM1 (0.43) | CARM1PRMT6FFAR1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL2787547 | 0.89 | CARM1 (0.42) | CARM1PRMT6FFAR1OPRK1 | |
| SCHEMBL754513 | 0.77 | ALDH1A1 (0.48) | CARM1PRMT6FFAR1OPRK1 | |
| SCHEMBL13166122 | 0.76 | CARM1 (0.41) | CARM1PRMT6FFAR1L3MBTL1 | |
| SCHEMBL13166120 | 0.75 | ALDH1A1 (0.45) | FFAR1L3MBTL1 | |
| SCHEMBL2787456 | 0.75 | CPB2 (0.47) | CARM1PRMT6 | |
| SCHEMBL13165750 | 0.75 | FFAR1 (0.42) | FFAR1L3MBTL1 | |
| SCHEMBL13165753 | 0.74 | CA12 (0.54) | — | |
| SCHEMBL13165744 | 0.73 | MEN1 (0.64) | CARM1PRMT6 | |
| SCHEMBL10121390 | 0.72 | ALDH1A1 (0.43) | FFAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |