Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 4/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165766 | 0.95 | MAPT (0.33) | UBE2MDCUN1D1OPRM1CCR2SCN9A | |
| SCHEMBL13166165 | 0.92 | UBE2M (0.34) | DDR2UBE2MDCUN1D1CCR2SCN9A | |
| SCHEMBL13165760 | 0.91 | CACNA1B (0.33) | DDR2UBE2MDCUN1D1OPRM1CCR2 | |
| SCHEMBL13165720 | 0.91 | CARM1 (0.33) | DDR2UBE2MDCUN1D1CCR2SCN9A | |
| SCHEMBL13165761 | 0.91 | BDKRB1 (0.33) | DDR2UBE2MDCUN1D1CCR2SCN9A | |
| SCHEMBL13165722 | 0.91 | SCN9A (0.35) | DDR2UBE2MDCUN1D1CCR2SCN9A | |
| SCHEMBL13165793 | 0.90 | MAPT (0.33) | DDR2UBE2MDCUN1D1CCR2SCN9A | |
| SCHEMBL13165643 | 0.89 | L3MBTL1 (0.38) | L3MBTL1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL13165764 | 0.89 | UBE2M (0.33) | DDR2UBE2MDCUN1D1OPRL1 | |
| SCHEMBL13165768 | 0.89 | OPRL1 (0.36) | DDR2UBE2MDCUN1D1CCR2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |