Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.55 |
| ▸ | TFPI | P10646 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 6/20 | 0.41 |
| ▸ | NPY1R | P25929 | 4/20 | 0.41 |
| ▸ | NPY2R | P49146 | 4/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463273 | 0.96 | SIRT5 (0.59) | SIRT5TFPINPY4RNPY1RNPY2R | |
| SCHEMBL13166808 | 0.96 | SIRT5 (0.59) | SIRT5TFPINPY4RNPY1RNPY2R | |
| SCHEMBL19084916 | 0.95 | SIRT5 (0.51) | SIRT5TFPIIL23REIF4EEIF4EBP1 | |
| SCHEMBL13701341 | 0.92 | SIRT5 (0.63) | SIRT5SIRT6SIRT1NPY4RNPY1R | |
| SCHEMBL15856928 | 0.91 | SIRT5 (0.54) | SIRT5TFPISIRT6SIRT1NPY4R | |
| SCHEMBL19084576 | 0.91 | SIRT5 (0.54) | SIRT5TFPIIL23RNPY4RNPY1R | |
| SCHEMBL31157731 | 0.91 | SIRT5 (0.51) | SIRT5TFPISIRT6SIRT1IL23R | |
| SCHEMBL31157691 | 0.91 | SIRT5 (0.51) | SIRT5TFPISIRT6SIRT1IL23R | |
| SCHEMBL30463245 | 0.91 | SIRT5 (0.51) | SIRT5TFPISIRT6SIRT1IL23R | |
| SCHEMBL30463240 | 0.91 | SIRT5 (0.51) | SIRT5TFPISIRT6SIRT1IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951103-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2018-04-24 | — | — | US | disclosed |
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2017-07-06 | — | — | US | disclosed |
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2017-07-06 | — | — | US | disclosed |
| US-9630991-B2 | βsheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2017-04-25 | — | — | US | disclosed |
| US-9630991-B2 | βsheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2017-04-25 | — | — | US | disclosed |
| US-20160046670-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2016-02-18 | — | — | US | disclosed |
| US-20160046670-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2016-02-18 | — | — | US | disclosed |
| US-9193764-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2015-11-24 | — | — | US | disclosed |
| US-9193764-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2015-11-24 | — | — | US | disclosed |
| US-9187527-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2015-11-17 | — | — | US | disclosed |
| US-9187527-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2015-11-17 | — | — | US | disclosed |
| US-20140186313-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20140186313-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20140044649-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2014-02-13 | — | — | US | disclosed |
| US-20140044649-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2014-02-13 | — | — | US | disclosed |
| US-8586539-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2013-11-19 | — | — | US | disclosed |
| US-20100234304-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS | 2010-09-16 | — | — | US | disclosed |
| US-20100234304-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046670-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | SIRT5 4719/4885TFPI 3734/4885SIRT6 4739/4885 |
| US-20140044649-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | SIRT5 4719/4885TFPI 3734/4885SIRT6 4739/4885 |
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | SIRT5 4719/4885TFPI 3734/4885SIRT6 4739/4885 |
| US-20140186313-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | SIRT5 4719/4885TFPI 3734/4885SIRT6 4739/4885 |
| US-20100234304-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | SIRT5 4719/4885TFPI 3734/4885SIRT6 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.