Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MAPK10 | P53779 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | CSF1R | P07333 | 6/20 | 0.97 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.76 |
| ▸ | ATM | Q13315 | 3/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13147762 | 0.99 | CSF1R (1.00) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL13148069 | 0.86 | CSF1R (1.00) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL3081171 | 0.84 | CSF1R (0.75) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL28379784 | 0.83 | MAPK10 (0.74) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL13147771 | 0.81 | HPGD (0.83) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL13148088 | 0.81 | CSF1R (1.00) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL13147776 | 0.81 | CSF1R (1.00) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL20623367 | 0.80 | CYP1A2 (0.69) | ALDH1A1MAPK10GAAHTTL3MBTL1 | |
| SCHEMBL13148038 | 0.79 | CSF1R (1.00) | ALDH1A1GAAHTTCSF1RMAPK1 | |
| SCHEMBL5093277 | 0.79 | CSF1R (1.00) | ALDH1A1GAAHTTCSF1RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | UGCG, MAGT1, STT3B | ALDH1A1 2578/4885MAPK10 1118/4885GAA 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.