Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13167244 | 0.91 | SMN1; SMN2 (0.38) | IDO1MEN1KMT2ASMN1; SMN2KDM1A | |
| SCHEMBL13167240 | 0.78 | NPC1 (0.38) | IDO1MEN1KMT2ASMN1; SMN2KDM1A | |
| SCHEMBL13167239 | 0.77 | KDM1A (0.49) | MEN1KMT2ASMN1; SMN2KDM1ALMNA | |
| SCHEMBL13167232 | 0.75 | KDM1A (0.46) | IDO1MEN1KMT2ASMN1; SMN2KDM1A | |
| SCHEMBL13167237 | 0.73 | TP53 (0.43) | IDO1MEN1KMT2ALMNAMAPT | |
| SCHEMBL13167235 | 0.73 | KDM1A (0.42) | MEN1KMT2ASMN1; SMN2KDM1ALMNA | |
| SCHEMBL13167234 | 0.70 | LMNA (0.47) | IDO1LMNAMAPTMAPK1TDP1 | |
| SCHEMBL13167229 | 0.70 | GAA (0.43) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL13134347 | 0.66 | MAPT (0.41) | MEN1KMT2ASMN1; SMN2KDM1ALMNA | |
| SCHEMBL23999258 | 0.60 | CA12 (0.61) | MEN1KMT2ASMN1; SMN2KDM1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799894-B2 | copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines | YAMAGUCHI UNIVERSITY (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20070120112-A1 | copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines | YAMAGUCHI UNIVERSITY (JP) | 2007-05-31 | — | — | US | disclosed |