Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13167232 | 0.84 | KDM1A (0.46) | KDM1AMEN1KMT2AMAPTLMNA | |
| SCHEMBL13167235 | 0.83 | KDM1A (0.42) | KDM1AMEN1KMT2AMAPTGAA | |
| SCHEMBL13167240 | 0.78 | NPC1 (0.38) | KDM1AMEN1KMT2AMAPTLMNA | |
| SCHEMBL13167237 | 0.77 | TP53 (0.43) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL13167243 | 0.77 | IDO1 (0.35) | KDM1AMEN1KMT2AMAPTLMNA | |
| SCHEMBL13167244 | 0.77 | SMN1; SMN2 (0.38) | KDM1AMEN1KMT2AMAPTLMNA | |
| SCHEMBL812440 | 0.76 | NQO2 (0.56) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL13167229 | 0.76 | GAA (0.43) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL13167234 | 0.73 | LMNA (0.47) | MAPTGAALMNAALDH1A1KDM4E | |
| SCHEMBL22134947 | 0.68 | KDM1A (0.49) | KDM1AMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799894-B2 | copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines | YAMAGUCHI UNIVERSITY (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20070120112-A1 | copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines | YAMAGUCHI UNIVERSITY (JP) | 2007-05-31 | — | — | US | disclosed |