Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749975 | 0.89 | MEN1 (0.60) | IDH1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL13023031 | 0.85 | DDX3X (0.60) | IDH1POLBKMT2AMEN1MAPT | |
| SCHEMBL13400526 | 0.85 | MAPT (0.51) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL13400497 | 0.84 | KCNK3 (0.56) | IDH1POLBKMT2AMEN1MAPT | |
| SCHEMBL12049693 | 0.83 | IDH1 (0.54) | IDH1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17409476 | 0.82 | SAE1 (0.64) | IDH1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL13132839 | 0.81 | HDAC3 (0.57) | IDH1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13132510 | 0.81 | NPC1 (0.55) | IDH1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL13132649 | 0.81 | NPC1 (0.55) | IDH1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL13023327 | 0.81 | HDAC3 (0.57) | IDH1KMT2AMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100079705-A1 | SUBSTRATE FOR LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2010-04-01 | — | — | US | disclosed |
| US-20100079705-A1 | SUBSTRATE FOR LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | IDH1 615/4885POLB 1474/4885KMT2A 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.