Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.64 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852140 | 0.84 | SAE1 (0.76) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL29703055 | 0.83 | SMN1; SMN2 (0.77) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL4416620 | 0.83 | SMN1; SMN2 (0.77) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL259602 | 0.82 | SMN1; SMN2 (0.75) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL17424508 | 0.82 | CYP2C9 (0.67) | KMT2ASMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31054278 | 0.82 | SMN1; SMN2 (0.75) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL13169441 | 0.82 | IDH1 (0.57) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL4748577 | 0.82 | CYP2C9 (0.56) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL22588905 | 0.81 | SAE1 (0.71) | SAE1UBA2KMT2ASMN1; SMN2PKM | |
| SCHEMBL22103910 | 0.80 | CNR1 (0.83) | SAE1UBA2KMT2ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |