Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 6/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540177 | 0.82 | ITGAV (0.43) | ACEITGB3ITGA2BMMEITGAV | |
| SCHEMBL11032508 | 0.80 | ACE (0.60) | ACEITGB3ITGA2BPTPN1MME | |
| SCHEMBL8657006 | 0.80 | ACE (0.60) | ACEITGB3ITGA2BPTPN1MME | |
| SCHEMBL9743083 | 0.74 | ACE (0.57) | ACEITGB3ITGA2BPTPN1ITGA4 | |
| SCHEMBL9743071 | 0.74 | ACE (0.57) | ACEITGB3ITGA2BPTPN1ITGA4 | |
| SCHEMBL30171991 | 0.73 | CXCR4 (0.45) | ITGB3ITGA2BCTSKITGAVITGB6 | |
| SCHEMBL5777591 | 0.73 | ACE (0.50) | ACEITGB3ITGA2BPTPN1ITGA4 | |
| SCHEMBL1920768 | 0.72 | ACE (0.54) | ACEITGB3ITGA2BPTPN1ITGA4 | |
| SCHEMBL14598327 | 0.71 | CTSS (0.56) | PTPN1CTSBCTSSCTSK | |
| SCHEMBL478774 | 0.71 | ACE (0.62) | ACEITGB3ITGA2BPTPN1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |