Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.48 |
| ▸ | ITGAV | P06756 | 17/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13170304 | 0.92 | ITGB1 (0.41) | ITGB3ITGAVALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7372792 | 0.90 | NPC1 (0.41) | ITGB3ITGAVALDH1A1MAPK1HSD17B10 | |
| SCHEMBL13170306 | 0.90 | ITGB3 (0.39) | ITGB3ITGAVALDH1A1MAPK1HSD17B10 | |
| SCHEMBL3050522 | 0.89 | PTPN1 (0.51) | ITGB3ITGAVIDO1 | |
| SCHEMBL7478067 | 0.89 | PTPN1 (0.44) | ITGB3ITGAVALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7441206 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7165492 | 0.88 | PTPN1 (0.44) | ITGB3ITGAVHSD17B10 | |
| SCHEMBL7371688 | 0.86 | ITGB3 (0.40) | ITGB3ITGAVALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7474158 | 0.86 | ITGB3 (0.48) | ITGB3ITGAVALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7163873 | 0.85 | ITGB3 (0.47) | ITGB3ITGAVALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |