Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371734 | 0.81 | PDGFRB (0.71) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL2931171 | 0.81 | KDM4E (0.71) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL3033147 | 0.80 | KDM4E (0.67) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL31287830 | 0.80 | KMT2A (0.72) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL1144832 | 0.79 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL15923772 | 0.79 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL2767179 | 0.79 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL9816433 | 0.79 | KDM4E (0.73) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL4369016 | 0.79 | PLA2G4A (0.67) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 | |
| SCHEMBL3641554 | 0.79 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101127-A1 | INDOLE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |