Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 8/20 | 0.45 |
| ▸ | TDO2 | P48775 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22395159 | 0.80 | EIF4A3 (0.57) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL29946251 | 0.80 | EIF4A3 (0.57) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL24113411 | 0.79 | GRIN1 (0.51) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL2492396 | 0.79 | IDO1 (0.51) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL20504988 | 0.76 | EIF4A3 (0.56) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL16065318 | 0.76 | GRIN2D (0.37) | KDM4EHPGDGRIN1ALDH1A1LMNA | |
| SCHEMBL2908763 | 0.75 | KDM4E (0.59) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL1957687 | 0.74 | KDM4E (0.53) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL19332395 | 0.73 | ULK1 (0.50) | EIF4A3KDM4EMEN1KMT2AFLT3 | |
| SCHEMBL13173650 | 0.73 | THRA (0.57) | EIF4A3IDO1TDO2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101127-A1 | INDOLE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |