Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TACR3 | P29371 | 10/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | TACR2 | P21452 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175636 | 0.92 | KDM5B (0.61) | MAPTTACR3THRBKDM5BTACR2 | |
| SCHEMBL13175715 | 0.90 | AKR1C3 (0.50) | MAPTTACR3KDM5BTACR2TACR1 | |
| SCHEMBL13175446 | 0.89 | THRB (0.51) | MAPTTACR3THRBKDM5BTACR2 | |
| SCHEMBL13175424 | 0.87 | AKR1C3 (0.48) | MAPTTACR3KDM5BTACR2TACR1 | |
| SCHEMBL13175686 | 0.86 | AKR1C3 (0.61) | MAPTTACR3THRBTACR2TACR1 | |
| SCHEMBL13175620 | 0.86 | TACR3 (0.58) | MAPTTACR3KDM5BTACR2TACR1 | |
| SCHEMBL13175438 | 0.85 | TACR3 (0.53) | MAPTTACR3KDM5BTACR2TACR1 | |
| SCHEMBL13175494 | 0.84 | AKR1C3 (0.46) | MAPTTACR3KDM5BTACR2TACR1 | |
| SCHEMBL13175948 | 0.83 | MEN1 (0.59) | MAPTTACR3KDM5BTACR2TACR1 | |
| SCHEMBL13175611 | 0.83 | AKR1C3 (0.51) | TACR3THRBKDM5BTACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |