Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.51 |
| ▸ | TACR3 | P29371 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175726 | 0.90 | ALPL (0.55) | AKR1C3L3MBTL1ALPLMAPTLMNA | |
| SCHEMBL13175732 | 0.89 | TACR3 (0.59) | AKR1C3L3MBTL1HTTMAPTLMNA | |
| SCHEMBL13175948 | 0.89 | MEN1 (0.59) | AKR1C3L3MBTL1MAPTSMN1; SMN2TACR3 | |
| SCHEMBL13175632 | 0.89 | AKR1C3 (0.59) | AKR1C3L3MBTL1ALPLMAPTLMNA | |
| SCHEMBL13175636 | 0.88 | KDM5B (0.61) | AKR1C3MAPTTACR3THRBTACR2 | |
| SCHEMBL13175455 | 0.88 | AKR1C3 (0.57) | AKR1C3LMNAUSP30TACR3TACR2 | |
| SCHEMBL13175454 | 0.88 | KDM5B (0.56) | AKR1C3ALPLMAPTLMNATACR3 | |
| SCHEMBL13175695 | 0.88 | LMNA (0.59) | AKR1C3MAPTLMNATACR3THRB | |
| SCHEMBL13175620 | 0.88 | TACR3 (0.58) | AKR1C3ALPLMAPTTACR3TACR2 | |
| SCHEMBL13175618 | 0.88 | AKR1C3 (0.59) | AKR1C3USP30TACR3TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |