Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28331816 | 0.84 | L3MBTL1 (0.56) | ALDH1A1POLBSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL5541680 | 0.79 | KDM4E (0.63) | ALDH1A1POLBSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL14330030 | 0.79 | GAA (0.59) | ALDH1A1POLBSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL5541669 | 0.76 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL11170826 | 0.76 | PIK3CG (0.43) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL23033213 | 0.76 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL1655937 | 0.76 | ESR1 (0.58) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL615340 | 0.76 | SMN1; SMN2 (0.58) | ALDH1A1POLBSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL21983971 | 0.76 | PIK3CG (0.61) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL2490866 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1POLBSMN1; SMN2GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067704-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |
| EP-1473333-B1 | INK-JET RECORDING INK AND METHOD OF INK-JET RECORDING | FUJIFILM CORP (JP) | 2010-09-22 | — | — | EP | disclosed |