Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098326 | 0.80 | POLB (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL21427839 | 0.73 | POLB (0.36) | ALDH1A1CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL16471907 | 0.71 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13178193 | 0.69 | TSHR (0.31) | ALDH1A1POLB | |
| SCHEMBL14145637 | 0.68 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL23010730 | 0.68 | ALDH1A1 (0.33) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9762672 | 0.68 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19860763 | 0.67 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL6139449 | 0.66 | — | — | |
| SCHEMBL11137074 | 0.66 | L3MBTL1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601384-B1 | METHODS OF RADIOFLUORINATION OF BIOLOGICALLY ACTIVE VECTORS | GE HEALTHCARE AS (NO) | 2010-09-22 | — | — | EP | disclosed |